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BI-D1870

CAT: 0957-S2843-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S2843-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM in cell-free assays, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3β, MARK3, CK1 and Aurora B. BI-D1870 exhibits anticancer attributes including the generation of reactive oxygen species (ROS) and increases in endoplasmic reticulum (ER) stress and autophagy.
CAS Number
501437-28-1
Target
S6 Kinase
Activity
MAPK
Molecular Formula
C19H23F2N5O2
Storage Conditions
2 years -80 in solvent

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