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Torin 2

CAT: 0957-S2817-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S2817-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Torin 2 is a potent and selective mTOR inhibitor with IC50 of 0.25 nM in p53−/− MEFs cell line; 800-fold greater selectivity for mTOR than PI3K and improved pharmacokinetic properties. Inhibition of ATM/ATR/DNA-PK with EC50 of 28 nM/35 nM/118 nM, in PC3 cell lines respectively. Torin 2 decreases cell viability and induces autophagy and apoptosis.
CAS Number
1223001-51-1
Target
ATM/ATR
Activity
PI3K/Akt/mTOR
Molecular Formula
C24H15F3N4O
Storage Conditions
2 years -80 in solvent

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