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MK-5108

CAT: 0957-S2770-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S2770-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MK-5108 is a highly selective Aurora A inhibitor with IC50 of 0.064 nM in a cell-free assay and is 220- and 190-fold more selective for Aurora A than Aurora B/C, while it inhibits TrkA with less than 100-fold selectivity. MK-5108 (VX-689) induces autophagy. Phase 1.
CAS Number
1010085-13-8
Synonyms
VX-689
Target
Aurora Kinase
Activity
Cell Cycle
Molecular Formula
C22H21ClFN3O3S
Storage Conditions
2 years -80 in solvent