Apitolisib (GDC-0980)

CAT: 0957-S2696-01Size: 5 mgDry Ice: YesHazardous: No

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CAT#:0957-S2696-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Apitolisib (GDC-0980, RG7422, GNE 390) is a potent, class I PI3K inhibitor for PI3Kα/β/δ/γ with IC50 of 5 nM/27 nM/7 nM/14 nM in cell-free assays, respectively. Also a mTOR inhibitor with Ki of 17 nM in a cell-free assay, and highly selective versus other PIKK family kinases. Apitolisib activates autophagy and apoptosis simultaneously in pancreatic cancer cells. Phase 2.

CAS Number

1032754-93-0

Synonyms

RG7422, GNE 390

Target

MTOR

Activity

PI3K/Akt/mTOR

Molecular Formula

C23H30N8O3S

Storage Conditions

2 years -80 in solvent

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205470	GDC-0980 (Apitolisib)
C08789-5mg	Apitolisib (GDC-0980)
MBS576253	Apitolisib (GDC-0980, RG7422)
MBS384750-01	GDC-0980 (Apitolisib, RG7422)
A11023-2	GDC-0980 (Apitolisib, RG7422) 2mg
A11023-25	GDC-0980 (Apitolisib, RG7422) 25mg
2668-5	GDC-0980
B2184-5.1	GDC-0980 (RG7422)
A11023-100	GDC-0980 100mg
A11023-10	GDC-0980 10mg

Apitolisib (GDC-0980)

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