Products for Research Use Only

Anti-CD131 [BION-1]

CAT: 0013-GTR17859049Size: 0.2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR17859049Size:0.2 mg
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Description
Mouse monoclonal antibody to CD131
Product Name Alternative
CSF2RB; CD131; IL3RB; IL-3R common beta subunit; IL5RB; colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) ; SMDP5; Common Beta-Chain; CDw131; cytokine receptor common subunit beta; beta-c; CD131; Beta Common Chain
UniProt
P32927
Reactivity
Human
Immunogen
BALB/c mice were immunized intraperitonally with COS cells transfected DQP (Domain 4 of the common beta-chain) expression constructs. The immunizations were repeated 4 times at 2-week intervals. Four weeks after the final immunization, a mouse was boosted with COS transfectants intravenously. Three days later, splenocytes were harvested and fused with NS-1 myeloma cells. Hybridoma supernatants were screened on CHO DQP cells by flow cytometry, with untransfected CHO cells as a control. All antibodies were from single hybridoma clones as selected by a limiting dilution method. MoAbs were purified from ascites fluid or hybridoma supernatant by a protein A sepharose column.
Target
CD131
Clonality
Monoclonal
Clone
BION-1
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Concentration
1 mg/ml
Purity
Purified
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
Blocking, Functional Studies, IHC, IP, WB
Host or Source
Mouse
Preservative
PBS with 0.02% Proclin 300.
Isotype
Mouse IgG

UniProtKB · P32927

Cytokine receptor common subunit beta

IL3RB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P32927
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CSF2RB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q5JZI1, Q6ICE0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoproteinPhosphoprotein

Cellular component

Membrane

Molecular function

Receptor

Domain

RepeatSignalTransmembraneTransmembrane helix

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