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OSI-027

CAT: 0957-S2624-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S2624-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
OSI-027 (ASP4786, CERC 006, AEVI-006) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM in cell-free assays, and more than 100-fold selectivity observed for mTOR than PI3Kα, PI3Kβ, PI3Kγ or DNA-PK. OSI-027 induces autophagy in cancer cells.
CAS Number
936890-98-1
Synonyms
ASP4786, CERC 006, AEVI-006
Target
MTOR
Activity
PI3K/Akt/mTOR
Molecular Formula
C21H22N6O3
Storage Conditions
2 years -80 in solvent

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