LDLR Polyclonal Antibody

• Background :

  Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

• Synonyms :

  FH; FHC; LDLCQ2; Low-density lipoprotein receptor; LDL receptor; LDLR

• Gene ID :

  3949

• Swiss Prot :

  P01130

• Cellular Locus :

  Cytoplasm, Cell membrane

• Host :

  Rabbit

• Cross Reactivity :

  Human, Mouse

• Immunogen :

  781-860/860

• Target :

  LDLR

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human LDL-R

• Applications :

  WB, ELISA, FCM, IHC-P, IF (IHC-P)

• Purification :

  Purified by Protein A.

• Concentration :

  1µg/µl

• Dilution :

  WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL :

  3949

• Predicted Cross Reactivity :

  Rat, Dog, Cow, Pig, Horse, Rabbit, GuineaPig

• Cross Reactivity Details :

  Hamster