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Idelalisib (CAL-101)

CAT: 0957-S2226-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S2226-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Idelalisib (CAL-101) is a selective p110δ inhibitor with IC50 of 2.5 nM in cell-free assays; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR. Idelalisib also stimulates autophagy.
CAS Number
870281-82-6
Synonyms
GS-1101
Target
PI3K
Activity
PI3K/Akt/mTOR
Molecular Formula
C22H18FN7O
Storage Conditions
2 years -80 in solvent