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RAF265 (CHIR-265)

CAT: 0957-S2161-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S2161-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RAF265 (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM in cell-free assays. RAF265 (CHIR-265) induces cell cycle arrest and apoptosis. Phase 2.
CAS Number
927880-90-8
Target
Raf
Activity
MAPK
Molecular Formula
C24H16F6N6O
Storage Conditions
2 years -80 in solvent

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