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Raltegravir

CAT: 0957-S2005-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S2005-01Size:5 mg
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Description
Raltegravir is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM in cell-free assays, respectively. It shows greater than 1000-fold selectivity for HIV-1 IN over several related Mg2+-dependent enzyme such as HCV polymerase, HIV reverse transcriptase, HIV RNaseH and human α-, β-, γ-polymerases.
CAS Number
518048-05-0
Synonyms
MK-0518
Target
Integrase
Activity
Microbiology
Molecular Formula
C20H21FN6O5
Storage Conditions
2 years -80 in solvent