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Doramapimod (BIRB 796)

CAT: 0957-S1574-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S1574-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Doramapimod (BIRB 796) is a pan-p38 MAPK inhibitor with IC50 of 38 nM, 65 nM, 200 nM and 520 nM for p38α/β/γ/δ in cell-free assays, and binds p38α with Kd of 0.1 nM in THP-1 cells, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2.
CAS Number
285983-48-4
Target
P38 MAPK
Activity
MAPK
Molecular Formula
C31H37N5O3
Storage Conditions
2 years -80 in solvent

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A10148-10mM-DDoramapimod (BIRB-796) 10mM * 1mL in DMSO
D9023Doramapimod, Free Base (1-[5-tert-butyl-2- (4-methylphenyl) pyrazol-3-yl]-3-[4- (2-morpholin-4-ylethoxy) naphthalen-1-yl]urea) (BIRB 796, DB03044, D03736)
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