Piroxicam

Chemical Information
Piroxicam is a monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide with the exocyclic nitrogen of 2-aminopyridine. A non-steroidal anti-inflammatory drug of the oxicam class, it is used to relieve pain and works by preventing the production of endogenous prostaglandins involved in the mediation of pain, stiffness, tenderness and swelling. It has a role as a non-steroidal anti-inflammatory drug, an analgesic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, an antirheumatic drug and a cyclooxygenase 1 inhibitor. It is a member of pyridines, a monocarboxylic acid amide and a benzothiazine.
| CAS Number | 36322-90-4 |
| PubChem CID | 54676228 |
| IUPAC Name | 4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-yl-1lambda6,2-benzothiazine-3-carboxamide |
| Molecular Formula | C15H13N3O4S |
| Molecular Weight | 331.3 |
| XLogP | 3.1 |
| Topological Polar Surface Area | 108 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 2 |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 611 |
| Property | Value |
|---|---|
| Molecular Weight | 331.3 |
| XLogP3 | 3.1 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 2 |
| Exact Mass | 331.06267708 |
| Monoisotopic Mass | 331.06267708 |
| Topological Polar Surface Area | 108 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 611 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Alternative Products
| Catalog | Name |
|---|---|
| AR-P02145-01 | Piroxicam |
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