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Piroxicam

CAT: 0024-sc-200576ASize: 5 gDry Ice: NoHazardous: No
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CAS Number
36322-90-4

Chemical Information

Piroxicam

Piroxicam is a monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide with the exocyclic nitrogen of 2-aminopyridine. A non-steroidal anti-inflammatory drug of the oxicam class, it is used to relieve pain and works by preventing the production of endogenous prostaglandins involved in the mediation of pain, stiffness, tenderness and swelling. It has a role as a non-steroidal anti-inflammatory drug, an analgesic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, an antirheumatic drug and a cyclooxygenase 1 inhibitor. It is a member of pyridines, a monocarboxylic acid amide and a benzothiazine.

CAS Number36322-90-4
PubChem CID54676228
IUPAC Name4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-yl-1lambda6,2-benzothiazine-3-carboxamide
Molecular FormulaC15H13N3O4S
Molecular Weight331.3
XLogP3.1
Topological Polar Surface Area108
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Heavy Atom Count23
Formal Charge0
Complexity611
SMILES
CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3
InChI
InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)
InChIKey
QYSPLQLAKJAUJT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Piroxicam
CAS: 36322-90-4
CID: 54676228
Formula: C15H13N3O4S
MW: 331.3
Interactive 3D Structure
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Computed Properties
PropertyValue
Molecular Weight331.3
XLogP33.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass331.06267708
Monoisotopic Mass331.06267708
Topological Polar Surface Area108 Ų
Heavy Atom Count23
Formal Charge0
Complexity611
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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