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Ruxolitinib

CAT: 0957-S1378-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S1378-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ruxolitinib is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis.
CAS Number
941678-49-5
Synonyms
INCB018424
Target
JAK
Activity
Angiogenesis
Molecular Formula
C17H18N6
Storage Conditions
2 years -80 in solvent

Alternative Products

CatalogName
RM-R241201-01Ruxolitinib Impurity A (Ruxolitinib Enantiomer)
tlrl-ruxRuxolitinib

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