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Rigosertib (ON-01910)

CAT: 0957-S1362-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S1362-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM in a cell-free assay. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells. Phase 3.
CAS Number
1225497-78-8
Target
PLK
Activity
Cell Cycle
Molecular Formula
C21H24NNaO8S
Storage Conditions
2 years -80 in solvent

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Alternative Products

CatalogName
MBS130460-01Rigosertib (ON-01910)
MBS385857-01ON-01910 (rigosertib)
A10673-5(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 5mg
A10673-100(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 100mg
A10673-10(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 10mg
A10673-50(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 50mg
A10673-25(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 25mg
A10673-2(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 2mg
A10673-10mM-D(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 10mM * 1mL in DMSO
E1KS1362ON-01910

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