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Ivermectin

CAT: 0957-S1351-01Size: 50 mgDry Ice: YesHazardous: No
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CAT#:0957-S1351-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ivermectin is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug. Ivermectin (MK-933, IVM) is a specific positive allosteric effector of P2X4 and α7 nicotinic acetylcholine receptors (nAChRs) . Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. Ivermectin induces autophagy through the AKT/mTOR signaling pathway and mitophagy.
CAS Number
70288-86-7
Synonyms
MK-933
Target
Chloride Channel
Activity
Transmembrane Transporters
Molecular Formula
C48H74O14
Storage Conditions
2 years -80 in solvent

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