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Camptothecin (CPT)

CAT: 0957-S1288-01Size: 100 mgDry Ice: YesHazardous: No
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CAT#:0957-S1288-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Camptothecin (CPT) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2.
CAS Number
7689-03-4
Synonyms
Campathecin, (S) - (+) -Camptothecin, NSC-100880
Target
Topoisomerase
Activity
DNA Damage/DNA Repair
Molecular Formula
C20H16N2O4
Storage Conditions
2 years -80 in solvent