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Amuvatinib (MP-470)

CAT: 0957-S1244-01Size: 2 mgDry Ice: YesHazardous: No
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CAT#:0957-S1244-01Size:2 mg
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Description
Amuvatinib (MP-470, HPK 56) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. Amuvatinib suppresses c-MET and c-RET. Amuvatinib is also active as a DNA repair protein Rad51 inhibitor with antineoplastic activity. Phase 2.
CAS Number
850879-09-3
Synonyms
HPK 56
Target
C-Kit
Activity
Protein Tyrosine Kinase
Molecular Formula
C23H21N5O3S
Storage Conditions
2 years -80 in solvent

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