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Lenvatinib

CAT: 0957-S1164-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S1164-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lenvatinib is a multi-target inhibitor, mostly for VEGFR2 (KDR) /VEGFR3 (Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β in cell-free assays. Lenvatinib (E7080) also inhibits FGFR1-4, PDGFR, Kit (c-Kit), RET (c-RET), and shows potent antitumor activities. Phase 3.
CAS Number
417716-92-8
Synonyms
E7080
Target
VEGFR
Activity
Protein Tyrosine Kinase
Molecular Formula
C21H19ClN4O4
Storage Conditions
2 years -80 in solvent

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