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Alisertib (MLN8237)

CAT: 0957-S1133-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S1133-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Alisertib (MLN8237) is a selective Aurora A inhibitor with IC50 of 1.2 nM in a cell-free assay. It has >200-fold higher selectivity for Aurora A than Aurora B. Alisertib induces cell cycle arrest, apoptosis and autophagy. Phase 3.
CAS Number
1028486-01-2
Target
Aurora Kinase
Activity
Cell Cycle
Molecular Formula
C27H20ClFN4O4
Storage Conditions
2 years -80 in solvent