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Crizotinib

CAT: 0957-S1068-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S1068-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Crizotinib is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM in cell-based assays, respectively. It is also a potent ROS1 inhibitor with Ki value less than 0.025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines.
CAS Number
877399-52-5
Synonyms
PF-02341066
Target
ALK
Activity
Protein Tyrosine Kinase
Molecular Formula
C21H22Cl2FN5O
Storage Conditions
2 years -80 in solvent

Alternative Products

CatalogName
T1661-01Crizotinib
A3020-100(R)-Crizotinib
A8802-50(S)-Crizotinib

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