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Olaparib (AZD2281)

CAT: 0957-S1060-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S1060-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations.
CAS Number
763113-22-0
Synonyms
Ku-0059436
Target
PARP
Activity
DNA Damage/DNA Repair
Molecular Formula
C24H23FN4O3
Storage Conditions
2 years -80 in solvent