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Sunitinib malate

CAT: 0957-S1042-01Size: 100 mgDry Ice: YesHazardous: No
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CAT#:0957-S1042-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sunitinib malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM in cell-free assays, and also inhibits c-Kit. Sunitinib Malate effectively inhibits autophosphorylation of Ire1α. Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis.
CAS Number
341031-54-7
Synonyms
SU11248 malate
Target
C-Kit
Activity
Protein Tyrosine Kinase
Molecular Formula
C22H27FN4O2.C4H6O5
Storage Conditions
2 years -80 in solvent

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