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Lenalidomide

CAT: 0957-S1029-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S1029-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lenalidomide is a TNF-α secretion inhibitor with IC50 of 13 nM in PBMCs. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis.
CAS Number
191732-72-6
Synonyms
CC-5013
Target
TNF-alpha
Activity
Apoptosis
Molecular Formula
C13H13N3O3
Storage Conditions
2 years -80 in solvent

Alternative Products

CatalogName
FL24864-01Lenalidomide

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