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Cediranib (AZD2171)

CAT: 0957-S1017-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S1017-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cediranib (AZD2171, NSC-732208) is a highly potent VEGFR (KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3 in HUVEC cells. Cediranib (AZD2171) induces autophagic vacuole accumulation. Phase 3.
CAS Number
288383-20-0
Synonyms
NSC-732208
Target
VEGFR
Activity
Protein Tyrosine Kinase
Molecular Formula
C25H27FN4O3
Storage Conditions
2 years -80 in solvent

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