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Bosutinib

CAT: 0957-S1014-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S1014-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bosutinib is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM in cell-free assays, respectively. Bosutinib also effectively decreases the activity of PI3K/AKT/mTOR, MAPK/ERK and JAK/STAT3 signaling pathways by blocking the phosphorylation levels of p-ERK, p-S6, and p-STAT3. Bosutinib promotes autophagy.
CAS Number
380843-75-4
Synonyms
SKI-606
Target
Src
Activity
Protein Tyrosine Kinase
Molecular Formula
C26H29Cl2N5O3
Storage Conditions
2 years -80 in solvent

Alternative Products

CatalogName
HY-10158-01Bosutinib
HY-10158SBosutinib-d8

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