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ABT-737

CAT: 0957-S1002-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S1002-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively; no inhibition observed against Mcl-1, Bcl-B or Bfl-1. ABT-737 induces mitochondrial pathway apoptosis and mitophagy. Phase 2.
CAS Number
852808-04-9
Target
Bcl-2
Activity
Apoptosis
Molecular Formula
C42H45ClN6O5S2
Storage Conditions
2 years -80 in solvent

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