EphB2 Polyclonal Antibody

CAT: 0498-bs-0247R-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0498-bs-0247R-01Size:20 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex. Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk. In addition to axon guidance, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses. Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation. Controls other aspects of development including angiogenesis, palate development and in inner ear development through regulation of endolymph production. Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca. May function as a tumor suppressor.
Synonyms
DRT; EK5; ERK; CAPB; Hek5; PCBC; EPHT3; Tyro5; Ephrin type-B receptor 2; Developmentally-regulated Eph-related tyrosine kinase; ELK-related tyrosine kinase; EPH tyrosine kinase 3; EPH-like kinase 5; Renal carcinoma antigen NY-REN-47; Tyrosine-protein kinase TYRO5; Tyrosine-protein kinase receptor EPH-3; EPHB2; EPTH3
Gene ID
2048
Swiss Prot
P29323
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
101-200/1055
Target
EphB2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human EphB2 R
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
2048
Predicted Cross Reactivity
Dog, Chicken

Related Products

CatalogName
bsm-51269MEPHB2 (8C4) Monoclonal Antibody
BIO0154SM-1mgAnti-human EphB2 (Genentech patent Anti-EphB2 Biosimilar)
BIO0154SM-5mgAnti-human EphB2 (Genentech patent Anti-EphB2 Biosimilar)
BIO0154SM-20mgAnti-human EphB2 (Genentech patent Anti-EphB2 Biosimilar)
bs-3880REPHX2 Polyclonal Antibody
bs-2571REphB6 Polyclonal Antibody
bs-25280REPHB6 Polyclonal Antibody
bs-0485R-01EphA2 Polyclonal Antibody
bs-10209REPHA2 Polyclonal Antibody
bs-0485R-TREphA2 Polyclonal Antibody

Alternative Products

CatalogName
MBS8592187-01EphB2 Polyclonal Antibody
35-1864-100Polyclonal Antibody to EPHB2
APRab10527-01EphB2 Rabbit Polyclonal Antibody
NBP2-56605Rabbit Polyclonal EphB2 Antibody
TMAB-00625-01Anti-EphB2 Polyclonal Antibody
NB100-55398Goat Polyclonal EphB2 Antibody

Popular Products