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Apilimod mesylate

CAT: 0957-S0785-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S0785-01Size:5 mg
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Description
Apilimod mesylate is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases. Apilimod mesylate (STA-5326 mesylate) inhibits IL-12 with IC50 of 1 nM, 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs, human monocytes and mouse PBMCs, respectively. Apilimod mesylate (STA-5326 mesylate) is also a cell permeable small molecule that specifically inhibits PIKfyve with IC50 of 14 nM.
CAS Number
870087-36-8
Synonyms
STA-5326 mesylate
Target
Interleukins
Activity
Immunology & Inflammation
Molecular Formula
C25H34N6O8S2
Storage Conditions
3 years -20°C powder

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