Leptin Receptor Polyclonal Antibody

• Background:

  Receptor for obesity factor (leptin) . On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity) .

• Synonyms:

  OBR; OB-R; CD295; LEP-R; LEPRD; Leptin receptor; HuB219; OB receptor; LEPR; DB; LEPR_MOUSE

• Gene ID:

  3953

• Swiss Prot:

  P48357

• Cellular Locus:

  Secreted, Cell membrane

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat

• Immunogen:

  901-1000/1165

• Target:

  Leptin receptor (Isoform B)

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human Leptin receptor:901-1000/1165

• Applications:

  WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification:

  Purified by Protein A.

• Concentration:

  1µg/µl

• Dilution:

  WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Specificity:

  This antibody will recognize the Isoform B variant only

• Gene ID URL:

  3953

• Predicted Cross Reactivity:

  Dog, Cow, Sheep, Pig