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Olverembatinib

CAT: 0957-E7062Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E7062Size:5 mg
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Description
Olverembatinib (GZD824, HQP1351) is an orally bioavailable inhibitor of pan-Bcr-Abl. It effectively inhibits a wide range of Bcr-Abl mutants, with IC50 of 0.34 nM and 0.68 nM for native Bcr-Abl and the Bcr-AblT315I mutant, respectively. It also induces tumor regression in mouse xenograft models.
CAS Number
1257628-77-5
Synonyms
GZD824, HQP1351
Target
Bcr-Abl
Activity
Protein Tyrosine Kinase
Molecular Formula
C29H27F3N6O

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