Products for Research Use Only
RegisterLogin

Sivelestat sodium

CAT: 0957-E6013-02Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0957-E6013-02Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Sivelestat sodium (ONO-5046, Sodium sivelestat, LY544349 sodium) is a potent, specific, and intravenously active inhibitor of neutrophil elastase with an IC50 value of 44 nm. It is a useful agent for studying the roles of neutrophil elastase in animal disease models such as emphysema, adult respiratory distress syndrome, septic shock and disseminated intravascular coagulation in COVID-19.
CAS Number
150374-95-1
Synonyms
ONO-5046, Sodium sivelestat, LY544349 sodium
Target
Serine Protease
Activity
Proteases
Molecular Formula
C20H21N2NaO7S

Chemical Information

sivelestat sodium anhydrous
CAS Number150374-95-1
PubChem CID23664980
IUPAC Namesodium 2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate
Molecular FormulaC20H21N2NaO7S
Molecular Weight456.4
Topological Polar Surface Area150
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count9
Heavy Atom Count31
Formal Charge0
Complexity738
SMILES
CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].[Na+]
InChI
InChI=1S/C20H22N2O7S.Na/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24;/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24);/q;+1/p-1
InChIKey
ZAIFANJZUGNYCK-UHFFFAOYSA-M
Chemical Structure
2D Structure
2D structure of sivelestat sodium anhydrous
CAS: 150374-95-1
CID: 23664980
Formula: C20H21N2NaO7S
MW: 456.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight456.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count9
Exact Mass456.09671647
Monoisotopic Mass456.09671647
Topological Polar Surface Area150 Ų
Heavy Atom Count31
Formal Charge0
Complexity738
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
S8136-01Sivelestat
S8136-10mM/1mLSivelestat
S8136-200mgSivelestat
S8136-1gSivelestat
S8136-10mgSivelestat
S8136-50mgSivelestat
E6751Sodium iodoacetate (Iodoacetic acid sodium salt)
E7036-1gDitiocarb sodium
E6061-01Cefamandole sodium
E6061-100mgCefamandole sodium

Alternative Products

CatalogName
466150-01Sivelestat Sodium
HY-17443A-01Sivelestat (sodium)
B8201-100Sivelestat sodium tetrahydrate
A4430-10Sivelestat sodium salt
A16137-10Sivelestat sodium 10mg

Popular Products