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EZH2/HSP90-IN-29

CAT: 0957-E4678-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E4678-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EZH2/HSP90-IN-29 is a potent dual inhibitor of EZH2 and HSP90, with IC50s of 6.29 nM and 60.1 nM, for EZH2 and HSP90, respectively, that induces M-phase cell cycle arrest, promotes apoptosis/necrosis-related gene expression, and inhibits ROS catabolism. It crosses the blood-brain barrier and can show potential as a tractable anti-GBM agent for glioblastoma research.
CAS Number
3033571-35-3
Target
EZH1/2
Activity
Epigenetics
Molecular Formula
C40H48N4O6

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