Products for Research Use Only
RegisterLogin

MK2-IN-1 hydrochloride

CAT: 0957-E2407Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0957-E2407Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MK2-IN-1 hydrochloride is a potent and selective MAPKAP-K2 (MK2) inhibitor with IC50 of 0.11 μM with a non-ATP competitive binding mode.
CAS Number
1314118-94-9
Target
MAPKAPK2
Activity
MAPK
Molecular Formula
C27H25ClN4O2.ClH
Storage Conditions
3 years -20°C powder

Chemical Information

MK2-IN-1 hydrochloride
CAS Number1314118-94-9
PubChem CID70681199
IUPAC Name5-(4-chlorophenyl)-N-(4-piperazin-1-ylphenyl)-N-(pyridin-2-ylmethyl)furan-2-carboxamide;hydrochloride
Molecular FormulaC27H26Cl2N4O2
Molecular Weight509.4
Topological Polar Surface Area61.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count35
Formal Charge0
Complexity645
SMILES
C1CN(CCN1)C2=CC=C(C=C2)N(CC3=CC=CC=N3)C(=O)C4=CC=C(O4)C5=CC=C(C=C5)Cl.Cl
InChI
InChI=1S/C27H25ClN4O2.ClH/c28-21-6-4-20(5-7-21)25-12-13-26(34-25)27(33)32(19-22-3-1-2-14-30-22)24-10-8-23(9-11-24)31-17-15-29-16-18-31;/h1-14,29H,15-19H2;1H
InChIKey
AZDOSXSDARWKGX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of MK2-IN-1 hydrochloride
CAS: 1314118-94-9
CID: 70681199
Formula: C27H26Cl2N4O2
MW: 509.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight509.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass508.1432815
Monoisotopic Mass508.1432815
Topological Polar Surface Area61.6 Ų
Heavy Atom Count35
Formal Charge0
Complexity645
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
S6930-01MK2 Inhibitor III
S6930-25mgMK2 Inhibitor III
S6930-100mgMK2 Inhibitor III
S6930-5mgMK2 Inhibitor III
S6930-1gMK2 Inhibitor III
S4891-25mg1-Aminohydantoin Hydrochloride
E5843-100mgPDK4-IN-1 hydrochloride
S4891-011-Aminohydantoin Hydrochloride
E5843-25mgPDK4-IN-1 hydrochloride
E5843-01PDK4-IN-1 hydrochloride

Alternative Products

CatalogName
HY-12834A-01MK2-IN-1 (hydrochloride)
T4442-01MK2-IN-1 hydrochloride
A21662-25MK2-IN-1 hydrochloride 25mg
A21662-100MK2-IN-1 hydrochloride 100mg
A21662-5MK2-IN-1 hydrochloride 5mg
A21662-200MK2-IN-1 hydrochloride 200mg
A21662-50MK2-IN-1 hydrochloride 50mg
A21662-10MK2-IN-1 hydrochloride 10mg
A21662-10mM-DMK2-IN-1 hydrochloride 10mM * 1mL in DMSO
XAA583291,1-Dimethylguanidine hydrochloride

Popular Products