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Emvododstat (PTC299)

CAT: 0957-E1078Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E1078Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Emvododstat (PTC299), a post-transcriptional inhibitor of pathogenic VEGF and dihydroorotate dehydrogenase (DHODH), inhibits VEGFA mRNA translation and abnormal cell proliferation. In HeLa cells PTC299 inhibits hypoxia-induced VEGFA protein production with an EC50 of 1.64 nM.
CAS Number
1256565-36-2
Target
Dehydrogenase
Activity
Metabolism
Molecular Formula
C25H20Cl2N2O3
Storage Conditions
3 years -20°C powder