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IMP-1088

CAT: 0957-E0428-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E0428-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IMP-1088 is a potent dual inhibitor of human N-myristoyltransferases NMT1 and NMT2, with an IC50 of <1 nM for HsNMT1 and HsNMT2 and a Kd of <210 pM for HsNMT1. It effectively inhibits the production of infectious rhinovirus virions by blocking the N-myristoylation of the rhinovirus VP0 protein.
CAS Number
2059148-82-0
Target
Others
Activity
Others
Molecular Formula
C25H29F2N5O

Chemical Information

Imp-1088
CAS Number2059148-82-0
PubChem CID132274735
IUPAC Name1-[5-[3,4-difluoro-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-1-methylindazol-3-yl]-N,N-dimethylmethanamine
Molecular FormulaC25H29F2N5O
Molecular Weight453.5
XLogP4.3
Topological Polar Surface Area48.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Heavy Atom Count33
Formal Charge0
Complexity642
SMILES
CC1=C(C(=NN1C)C)CCOC2=C(C=CC(=C2F)F)C3=CC4=C(C=C3)N(N=C4CN(C)C)C
InChI
InChI=1S/C25H29F2N5O/c1-15-18(16(2)31(5)28-15)11-12-33-25-19(8-9-21(26)24(25)27)17-7-10-23-20(13-17)22(14-30(3)4)29-32(23)6/h7-10,13H,11-12,14H2,1-6H3
InChIKey
SOXNKJCQBRQUMS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Imp-1088
CAS: 2059148-82-0
CID: 132274735
Formula: C25H29F2N5O
MW: 453.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight453.5
XLogP34.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass453.23401689
Monoisotopic Mass453.23401689
Topological Polar Surface Area48.1 Ų
Heavy Atom Count33
Formal Charge0
Complexity642
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
T9350-01IMP-1088
GTR19210697-01CC-1088
HY-162778FM-1088
T9901A-511-01NTX-1088
MBS3846668-01MDK-1088
ABC-TC1178SW 1088
A22133-100MDK-1088 100mg
A22133-25MDK-1088 25mg
A22133-10MDK-1088 10mg
A22133-5MDK-1088 5mg

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