B7-H3/CD276 Recombinant Antibody

• Background:

  May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces.

• Synonyms:

  4Ig B7 H3; B7 homolog 3; B7H3; B7RP-2; CD276 antigen; CD276 molecule.

• Gene ID:

  80381

• Swiss Prot:

  Q5ZPR3

• Cellular Locus:

  Cell membrane

• Host:

  Rabbit

• Cross Reactivity:

  Human

• Target:

  B7-H3/CD276

• Clonality:

  Recombinant

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human CD276

• Applications:

  WB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF

• Purification:

  Purified by Protein A.

• Concentration:

  Lot dependent

• Dilution:

  WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IP (1-2ug), IF (), Flow-Cyt (1ug/Test), ICC/IF (1:50-100)

• Buffer:

  0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  80381

• Isotype:

  IgG