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Cilofexor (GS-9674)

CAT: 0957-S6547-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S6547-01Size:5 mg
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Description
Cilofexor (GS-9674) is a potent, selective oral agonist of farnesoid X receptor (FXR) with an EC50 of 43 nM. It has demonstrated anti-inflammatory, antifibrotic effects, and reduced portal pressure in preclinical liver fibrosis models, showing potential therapeutic benefit for primary sclerosing cholangitis (PSC) and nonalcoholic steatohepatitis (NASH) research.
CAS Number
1418274-28-8
Synonyms
GS-9674
Target
FXR
Activity
Metabolism
Molecular Formula
C28H22Cl3N3O5