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Mifepristone

CAT: 0957-S2606-01Size: 50 mgDry Ice: YesHazardous: No
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CAT#:0957-S2606-01Size:50 mg
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Description
Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.Mifepristone (RU486) can be used to induce animal models of Spontaneous Abortion.
CAS Number
84371-65-3
Synonyms
C-1073, RU 38486
Target
Estrogen/progestogen Receptor
Activity
Endocrinology & Hormones
Molecular Formula
C29H35NO2
Storage Conditions
2 years -80 in solvent

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