NEDD8 Recombinant Antibody, PE Conjugated

• Background:

  Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis via its conjugation to a limited number of cellular proteins, such as cullins or p53/TP53.Attachment of NEDD8 to cullins is critical for the recruitment of E2 to the cullin-RING-based E3 ubiquitin-protein ligase complex, thus facilitating polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.

• Synonyms:

  NEDD8; Nedd-8.

• Gene ID:

  4738

• Swiss Prot:

  Q15843

• Cellular Locus:

  Nucleus

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat

• Target:

  NEDD8

• Clonality:

  Recombinant

• Conjugation:

  PE

• Source:

  KLH conjugated synthetic peptide derived from human NEDD8

• Applications:

  WB, IF

• Purification:

  Purified by Protein A.

• Excitation Emission:

  496,564nm/578nm

• Concentration:

  Lot dependent

• Dilution:

  WB (1:300-5000), IF ()

• Buffer:

  Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

• Gene ID URL:

  4738

• Isotype:

  IgG