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Hispidulin

CAT: 0957-S3296Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0957-S3296Size:1 mg
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Description
Hispidulin (Dinatin), an active natrual ingredient in a number of traditional Chinese medicinal herbs, exhibits inhibitory activity against the oncogenic protein kinase Pim-1 with IC50 of 2.71 μM. Hispidulin induces apoptosis through mitochondrial dysfunction and inhibition of P13k/Akt signalling pathway in HepG2 cancer cells. Hispidulin exerts anti-osteoporotic and bone resorption attenuating effects via activating the AMPK signaling pathway.
CAS Number
1447-88-7
Synonyms
Dinatin
Target
Pim
Activity
JAK/STAT
Molecular Formula
C16H12O6
Storage Conditions
3 years -20°C powder

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