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Bemcentinib (R428)

CAT: 0957-S2841-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0957-S2841-01Size:1 mg
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Description
Bemcentinib (R428, BGB324) is an inhibitor of Axl with IC50 of 14 nM, >100-fold selective for Axl versus Abl. Selectivty for Axl is also greater than Mer and Tyro3 (50-to-100- fold more selective) and InsR, EGFR, HER2, and PDGFRβ (100- fold more selective) .
CAS Number
1037624-75-1
Synonyms
BGB324
Target
Axl
Activity
Protein Tyrosine Kinase
Molecular Formula
C30H34N8
Storage Conditions
2 years -80 in solvent