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Itraconazole

CAT: 0957-S2476-01Size: 200 mgDry Ice: YesHazardous: No
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CAT#:0957-S2476-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Itraconazole is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy.
CAS Number
84625-61-6
Synonyms
R 51211
Target
Hedgehog/Smoothened
Activity
Stem Cells & Wnt
Molecular Formula
C35H38Cl2N8O4
Storage Conditions
2 years -80 in solvent

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