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Vemurafenib (PLX4032)

CAT: 0957-S1267-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S1267-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vemurafenib (PLX4032, RG7204, RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold. Vemurafenib (PLX4032, RG7204) induces autophagy.
CAS Number
918504-65-1
Synonyms
RG7204, RO5185426, PLX4032
Target
Raf
Activity
MAPK
Molecular Formula
C23H18ClF2N3O3S
Storage Conditions
3 years -20°C (in the dark) powder1 year -80°C (in the dark) in solvent

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