Products for Research Use Only
RegisterLogin

Alsterpaullone

CAT: 0957-S0354Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0957-S0354Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Alsterpaullone (Alp, 9-Nitropaullone, NSC 705701) is a potent inhibitor of CDK with IC50 of 35 nM, 15 nM, 200 nM and 40 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E and CDK5/p35, respectively. Alsterpaullone also acts as a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50 of both 4 nM for GSK-3α and GSK-3β. Alsterpaullone induces apoptosis by activation of caspase-9. Alsterpaullone has antitumor activity and possesses potential for the treatment of neurodegenerative and proliferative disorders.
CAS Number
237430-03-4
Synonyms
Alp, 9-Nitropaullone, NSC 705701
Target
CDK
Activity
Cell Cycle
Molecular Formula
C16H11N3O3
Storage Conditions
3 years -20°C powder

Alternative Products

CatalogName
044496-01Alsterpaullone

Popular Products