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CD15 Antibody

CAT: 0013-GTR17858505Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR17858505Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD15 (Lewis x), also known as stage specific embryonic antigen-1 (SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le (x) antigen exhibit strong self-aggregation, based on calcium-dependent Le (x) -Le (x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le (x) and its isomer sialyl-Le (a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin ́s disease.
Product Name Alternative
Lewis x Blood Group antigen, Le (x), SSEA-1, 3-fucosyl-N-acetyllactosamine
Reactivity
Human
Immunogen
WERI-RB-1 retinoblastoma cell line
Target
CD15
Clonality
Monoclonal
Clone
W6D3
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Purified by protein-A affinity chromatography.
Concentration
1 mg/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Flow cytometry: Recommended dilution: 1-4 μg/ml
Tested Applications
FC
Preservative
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Isotype
Mouse IgG1 kappa
Entrez
35

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