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Mipomersen

CAT: 0957-E6581-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0957-E6581-01Size:1 mg
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Description
Mipomersen (ISIS 301012 free base) is an antisense oligonucleotide inhibitor of apolipoprotein B-100 (apoB-100) that causes selective degradation of apoB-100 mRNA, thereby inhibiting protein translation. This leads to reductions in low-density lipoprotein cholesterol (LDL-C) and other apoB-containing lipoprotein levels. Mipomersen is used as an adjunct treatment for homozygous familial hypercholesterolemia (FH) .
CAS Number
1000120-98-8
Synonyms
ISIS 301012 free base
Target
HCV
Activity
Microbiology

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