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Agerafenib (CEP-32496)

CAT: 0957-S8015Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S8015Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Agerafenib (CEP-32496) is a highly potent inhibitor of BRAF (V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret (c-Ret), PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. Phase 1/2.
CAS Number
1188910-76-0
Synonyms
RXDX-105
Target
CSF-1R
Activity
Protein Tyrosine Kinase
Molecular Formula
C24H22F3N5O5
Storage Conditions
2 years -80 in solvent