MARK2 Recombinant Antibody

• Background :

  MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule.stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be coexpressed in a number of selected cell lines and tissue samples. Human MARK2 was shown to be encoded by a single mRNA ubiquitously expressed. This transcription variant includes the alternative exon in the coding region and therefore codes for a longer protein. Multiple splice variants exist for this protein.

• Synonyms :

  Serine/threonine-protein kinase MARK2; ELKL motif kinase 1; MAP/microtubule affinity-regulating kinase 2; EMK-1; Par-1b; Par1b; MARK2; EMK1

• Gene ID :

  2011

• Swiss Prot :

  Q7KZI7

• Cellular Locus :

  Cytoplasm, Cell membrane, Cytoskeleton

• Host :

  Rabbit

• Cross Reactivity :

  Human, Mouse, Rat

• Target :

  MARK2

• Clonality :

  Recombinant

• Conjugation :

  Unconjugated

• Source :

  Recombinant protein near the C-terminus of human MARK2.

• Applications :

  WB, IHC-P, IHC-F, IF, Flow-Cyt

• Purification :

  Purified by Protein A.

• Concentration :

  1ug/ul

• Dilution :

  WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF (), Flow-Cyt (1ug/Test)

• Buffer :

  0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL :

  2011

• Isotype :

  IgG