Pociredir

CAT: 0804-HY-139400-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-139400-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Pociredir (FTX-6058) is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED) . Pociredir can induce HbF protein expression in cell and murine models. Pociredir can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia[1][2].

CAS Number

2490676-18-9

Product Name Alternative

FTX-6058

UNSPSC

12352005

Target

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/pociredir-1.html

Concentration

10mM

Purity

99.97

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC1=NC=CC=C1C2=CC(OC3)=C(NCC4=C(F)C=CC5=C4[C@@H]3CO5)N6C2=NN=C6

Molecular Formula

C22H18FN5O2

Molecular Weight

403.41

References & Citations

[1]Boerner LK. Virtual meeting delivers first time drug structures. April 12, 2021.|[2]Fulcrum Therapeutics Presents Published Structure of Investigational Small Molecule FTX-6058 at the American Chemical Society (ACS) Spring 2021 Virtual Conference.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

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