TXNRD1 Polyclonal Antibody

• Background:

  Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

• Synonyms:

  TR; TR1; TXNR; TRXR1; GRIM-12; Thioredoxin reductase 1, cytoplasmic; Gene associated with retinoic and interferon-induced mortality 12 protein; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-12-derived reductase-like factor; Thioredoxin reductase TR1; TXNRD1; GRIM12; KDRF

• Gene ID:

  7296

• Swiss Prot:

  Q16881

• Cellular Locus:

  Cytoplasm, Nucleus

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat

• Immunogen:

  451-550/649

• Target:

  TXNRD1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human TXNRD1

• Applications:

  WB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF

• Purification:

  Purified by Protein A.

• Concentration:

  1ug/ul

• Dilution:

  WB (WB=1:500-2000), IHC-P (IHC-P=1:50-200), IHC-F (IHC-F=1:50-200), IP (IP=1:20-50), IF (IF=1:50-200), Flow-Cyt (Flow-Cyt=1:20-50), ICC/IF (ICC/IF=1:50-200)

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Prediction Reactivity:

  Dog, Cow, Pig, Horse

• Gene ID URL:

  7296

• Isotype:

  IgG